Genetics and Genetics Disorder

Genome Editing

Genome editing with engineered nucleases (GEEN) is emergent type of Genetic Engineering. GEEN is the technology during which DNA is inserted, deleted or replaced within the genome. The emergence of highly versatile genome-editing technologies has provided investigators with the power to rapidly and economically introduce sequence-specific modifications into the genomes of a broad spectrum of cell types and organisms. It also promotes various changes in sub cellular level. Genome Editing itself also holds tremendous potential for treating the underlying various idiopathic genetic causes of certain diseases. The core technologies now most ordinarily used techniques to facilitate genome editing are clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription activator-like effector nucleases (TALENs), zinc-finger nucleases (ZFNs), and homing endonucleases or mega nucleases.